Abstract?
AIM:
To obtain the
prevalence and
risk factors of symptomatic
dry eye disease ( SDED ) among college
students in
China.?
METHODS:
Population-based
cross-sectional study.
Students in
Medical School of Lanzhou
University were approached. A
questionnaire was used to evaluate the
prevalence of SDED and its
risk factors. The
diagnosis of SDED was based on reported symptoms and was established if the participants reported “often” or “all the
time” once or more for 6-item
questionnaire. Positive tests included a
tear-
film breakup
time ( TBUT)≤10s and a
fluorescein staining score ( FSS ) ≥1. Demographic information and possible factors that may contribute to SDED were analyzed in a step-wise multivariate
logistic regression modelto assess
risk factors of SDED.?
RESULTS:
There were 1139 participants ( 84. 37%response rate ) have completed the
questionnaire, 475
males and 664
females aged 16-26y. The
prevalence of SDED was 18. 70% [95%
confidence interval ( CI)= 16. 59-20. 81]. A TBUT of ≤10s and a FSS≥1 were noted in 47. 67%(95% CI=44. 95-50. 57) and 13. 97%(95% CI=11. 95-15. 99) for all participants, respectively. The multivariate
regression analysis revealed the following
risk factorsdaily
reading time of≥4h(OR=1. 58,95% CI=1. 15-2. 18), daily
computer use of≥4h ( OR= 1. 52, 95% CI= 1. 02-2. 25), and constant
eyeglasses wearing (OR=1. 54,95%CI=1. 08-2. 13). The
female gender,
refractive surgery and
contact lens ( CLs) wearing were not
risk factors for SDED in this
analysis.?
CONCLUSION:
The
prevalence for SDED is high in
Chinese college
students. The
risk factors include daily
reading time of≥4h, daily
computer use of≥4h and constant
eyeglasses wearing.