Study Progress on Relationship of Transforming Growth Factor-?_1 and Airway Remodelig in Asthma / 实用儿科临床杂志
yu-mei, LI; cai-xia, AN; ying, ZHAO; bin, LI; ming-xia, GAO.
Journal of Applied Clinical Pediatrics
; (24)2006.
Artículo
en Zh
| WPRIM | ID: wpr-640054
Transforming growth factor-?1 (TGF-?1) was reported to play an important role in the pathogenesis of asthma in many stu-dies.It can stimulate the growth of fibroblast and give rise to fibrosis of lung tissues.Many scholars think that TGF-?1 is closely related to airway remodeling.It is a breakthrough to aim at TGF-?1 to find a way to intervene remodeling in asthma.Glucocorticoid (Dexamethasone and Budesonide) can have an impact in some extent to airway remodeling.In addition,interferon-? and some traditional chinese medicine such as ligustrazine,tripterygium wilfordii and ginkgo maybe effective,they all may ameliorate the progression of airway remodeling following redu-cing partial airway TGF-?1 expression.
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