In recent years,
cancer immunotherapy has developed rapidly due to its significant advantages compared with the traditional
cancer treatment methods.
Tumor immunotherapy aims at mobilizing or stimulating the body's own immune function,thereby inhibiting and
killing cancer cells.With the development of
nanotechnology,
biological nano-carrier materials provide a new insight into the
vaccine development.
Nano-vaccines are
therapeutic or prophylactic
vaccines based on
nanotechnology including exogenous
antigens for inducing
immune responses,vectors delivering
antigens,and adjuvants for enhancing immunogenicity and accelerating and prolonging the availability of
cancer vaccines.Nano-delivery vectors have good biocompatibility as well as unique
physical and chemical properties.They can effectively deliver the
antigens,and further activated the
immune response of antigenspecific cellulars based on the activation of the body's
humoral immunity by regulating the presentation pathways in the
antigen-presenting cells.In this
paper,the applications of nano-delivery systems in
cancer vaccine research were summarized.