Objective To explore the application of transbronchial
needle aspiration biopsy (EBUS-TBNA) combined with ultrasound
bronchoscopy under the
general anesthesia (
intravenous anesthesia combined with
laryngeal mask).
Methods 103
patients with EBUS-TBNA from June 2015 to October 2016 were randomly divided into
local anesthesia group and
general anesthesia group. The
anesthesia group was anesthetized with
intravenous anesthesia combined with
laryngeal mask,
local anesthesia group with conventional
tetracaine local anesthesia. The differences in the average number of
puncture needles, the
diagnosis rate, the operation
time, the
complications and the comfort of each group were analyzed retrospectively. Results The average number of
puncture needle in each group was 5.6 times, and the
local anesthesia group was 3.1 times. The
diagnosis rate of
general anesthesia group was 94.12% and
local anesthesia group was 78.85%. There was significant difference between the two groups (χ2 = 5.11, P = 0.024). The average operation
time in the
general anesthesia group was (14.61 ± 1.52), the
local anesthesia group was (32.52 ± 4.14), they had significant difference (t = 29.01, P = 0.000). The number of
patients in
bleeding and
cough of the
general anesthesia group were lower than those in the
local anesthesia group (χ2 = 4.31, 103.00, P = 0.038, 0.000, respectively). Conclusions EBUS-TBNA under
general anesthesia has high diagnostic rate, shortoperating
time, painlessness, high comfort and reduce operational
risk, worthy of promoting clinical application.