OBJECTIVE To compare two
administration methods of
triamcinolone acetonide cream for the
treatment of
ear mycosis with pevison.
METHODS Eighty-six cases diagnosed as the
external auditory canal fungal infections with
tympanic membrane perforation were randomly divided into
observation group and
control group, with 43 cases in each group. All the selected
patients were positive in the external auditory meatal
secretions fungus detection test,
fungi and
secretions of the
external auditory canal are thoroughly cleaned under the
endoscope. After
ear canal cleaning, the obervation group was treated with Pevisone smeared on
gelatin sponge which was evenly placed on the
external auditory canal with
fungal infection. The
control group was treated with Pevisone smearing on
external auditory canal by the
patients themselves, twice a day. Two groups of
patients come to the
hospital every 3 days for
review. After 2 weeks of
treatment, the
patients were followed up for 3 months, and the
clinical efficacy of each group was compared. RESULTS The
observation group was cured in 39 cases(90.7%), effective in 2 cases(4.7%), and ineffective in 2 cases(4.7%), The total
efficiency rate is 95.3%.1 case recurred at 3 months of follow-up(2.4%). While in the
control group, it was cured in 26 cases(60.5%), effective in 1 cases(2.3%), and ineffective in 16 cases(37.2%), the total
efficiency rate is 62.8%.9 cases recurred at 3 months of follow-up(31.0%). The effect of the
observation group was significantly higher than that of the
control group(x2=14.508, P<0.05). CONCLUSION The
ear endoscope can be used to remove the
external auditory canal fungus thoroughly and has good visibility. Treating
external auditory canal fungi disease with
tympanic membrane perforation with
gelatin sponge coated with
triamcinolone acetonide cream has better
clinical efficacy.