Objective To investigate the
effectiveness and
safety of AngioJet rheolytic
thrombectomy in the
treatment of acute
limb ischemia (ALI).
Methods The clinical data of a total of 19
patients with ALI of
lower limbs,
who were treated with AngioJet rheolytic
thrombectomy, were retrospectively analyzed. The
patients included 14
males and 5
females, with a mean age of (77.7±6.8)years old (66-90 years old). The
thrombus clearance rate ≥90% was defined as grade Ⅲ, 50%-90% as grade Ⅱ, and <50% as grade I, which was used to evaluate the
thrombus clearance effect. The postoperative
device-related complication,
amputation incidence and the
mortality were recorded. Results In all the 19
patients, the technical success rate was 100%. The
thrombus clearance rate after initial AngioJet rheolytic
thrombectomy was >50% in all
patients, among them grade Ⅲ was obtained in 14
patients (73.7%) and grade Ⅱ in 5
patients (26.3%). The symptoms of
lower extremity pain,
ischemia, etc. were improved. In 5
patients, macroscopic
hemoglobinuria occurred once after the
treatment. No serious
complications such as
bleeding at
puncture point,
hemorrhage of
digestive tract, renal function damage or
death occurred.
Limb salvage was achieved in17, with a
limb salvage rate of 89.5%, the 6-month and one-year
limb salvage rates were 84.6% (11/13) and 80.0% (8/10) respectively. Conclusion For the
treatment of ALI of
lower limbs, AngioJet rheolytic
thrombectomy is safe and effective, it can rapidly recover arterial
blood flow. AngioJet rheolytic
thrombectomy is especially suitable for the
elderly patients and the
patients who have high
risk for surgical operation or have
contraindications for thrombolysis.