Objective To explore the
risk factors of pulmonary
hemorrhage in
patients undergoing CT-guided percutaneous
lung biopsy.
Methods Data of 347
patients who underwent CT-guided percutaneous
lung biopsy were retrospectively reviewed.Clinical factors that might cause pulmonary
hemorrhage,including age,
gender,whether combine with
emphysema,main
pulmonary artery diameter,and whether or not taking
antiplatelet drugs,
puncture frequency,
needle angle,maximum diameter,morphology,as well as the distance between lesion and pleural were analyzed.Results Among 347
patients,168
patients developed pulmonary
hemorrhage after the
procedures (
hemorrhage group),including 25
patients with
hemoptyses and 1
patient with
hemopneumothorax.Compared with non
hemorrhage group,ratio of
female (P=0.010),of
emphysema (P=0.016) and of sub-solid lesions (P=0.036) were higher in
hemorrhage group,while lesions' diameter was smaller (P=0.003) and ratio of subpleural lesions was lower (P<0.001) in
hemorrhage group.The difference of pulmonary
hemorrhage ratio between
patients with enlarged main
pulmonary artery diameter at CT (≥2.9 cm) or not had no statistical significance (x2 = 0.011,P= 0.915).Conclusion Pulmonary
hemorrhage after CT-guided percutaneous
lung biopsy is common but rarely need clinical
treatment.Enlarged main
pulmonary artery diameter at CT (≥2.9 cm) is not the
risk factor of pulmonary
hemorrhage after
puncture.