Objective To investigate clinical and histopathological features of
lichen planopilaris (LPP).
Methods The clinical and histopathological findings in 3 cases of LPP were analyzed.Results All the 3
patients were
female,and their average age was 49 years.One
patient presented with large-area patchy
hair loss on the frontal,parietal and
occipital region,and 2
patients presented with irregular patchy
hair loss on the
scalp and
skin atrophy.Besides the
hair loss,the
eyebrows and axillary
hairs also lost in 1
patient.Histopathological examination showed
liquefaction degeneration of basal
cells in the walls of
hair follicles and infiltration of
lymphocytes.Infiltration of a small number of
lymphocytes was also observed around
blood vessels and appendages.Conclusions LPP may only
affect the
scalp,or involve the other sites all over the body.LPP commonly manifests as patchy
hair loss on the
scalp and
skin atrophy,and is pathologically characterized by
liquefaction degeneration of basal
cells in
hair follicles and infiltration of
lymphocytes.