Objective To explore the predictive value of
prognostic nutritional index (PNI) in
surgical site infections (SSIs) for
intestinal fistula patients undergoing bowel resections.
Methods Clinical data of 290 gastrointestinal
fistula patients who underwent intestinal resections between 2012 and 2015 were retrospectively reviewed.Univariate and
multivariate analyses were conducted to identify
risk factors for SSIs,and
receiver operating characteristic (ROC) curve was used to quantify the
effectiveness of PNI.Results SSIs were diagnosed in 99 (34.1%)
patients.
ROC curve analysis defined a PNI cut-off level of 45 corresponding to postoperative SSIs (area under the curve =0.72,76%
sensitivity,55%
specificity).Furthermore,a
multivariate analysis indicated that the PNI < 45 (OR2.24,95% CI1.09-4.61,P =0.029) and preoperative
leukocytosis (OR3.70,95 % CI1.02-13.42,P =0.046) were independently associated with postoperative SSIs.Conclusions Preoperative PNI is useful to predict SSIs in intestinal fistulae
patients after enterectomies.