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Ethambutol(EMB)has been used as first-line
antibiotics to treat
tuberculosis. Side effects of
ethambutol have been well documented since its original use, with the most serious one being
optic neuropathy. EMB-induced
optic neuropathy(EON)may be reversible in the early stages, but
delayed diagnosis has been shown to result in permanent visual loss. Thus the reversibility of EON is dependent on early
detection. In this
review, we discuss
risk factors,
detection methods,
treatment and prevention of EON.