Limited data are available on the efficacy of statintherapy in stable ischemic heart disease with chronic total occlusion (CTO) without revascularization. We investigated whether statintherapy could be beneficial in stable patients with CTO without revascularization.
METHODS:
From March 2003 to February 2012, 2,024 patients with at least one CTO were enrolled in a retrospective, single-center registry; 664 of these patients were managed conservatively without an initial revascularization strategy. Among them, we excluded CTO cases involving acute coronary syndrome, in-hospitaldeath or incomplete data and classified 551 patients into statin (n = 369) and non-statin (n = 182) groups according to use of statin at discharge. Propensity score matching analysis was also performed in 148 pairs. The primary outcome was cardiac death.