Canine adenovirus type 2 (CAV-2) is the cause of a major respiratory illness in
dogs. In this study, we analyzed
adenovirus infections in
dogs using 2000–2017 data from the
Animal and
Plant Quarantine Agency (APQA) and conducted a serological
survey of CAV-2
infection in six
animal species in
Korea. In total, 38 of the 3,179
dog samples were confirmed as
canine adenovirus infections. In serological
survey, 1,028
dog sera, 160
raccoon dog sera, 100
cattle sera, 257 sow sera, 206
horse sera, and 106
cat sera, collected from January 2016 to July 2018, were screened for the presence of anti-CAV-2
antibodies by
virus neutralization test. The seropositivity rates for
dogs, raccoon dogs,
cattle, sows,
horses, and
cats were 88.5% (910/1,028), 51.3% (82/160), 85.0% (85/100), 48.6% (125/257), 35.0% (72/206), and 2.8% (3/106), respectively. Among
dogs and
raccoon dogs, 1.9% (20/1,028) and 8.8% (14/160), respectively, had a
virus-
neutralizing antibody (VNA) titer of over 1256. A high CAV-2 VNA titer indicates a repeated
vaccination or natural
infection in Korean
dogs and circulation of CAV-2 in
raccoon dog populations.