The Improvement of Learning and Memory Ability of Normal Persons by BF-7
Sang-Hyung LEE; Yong-Sik KIM; Yong-Koo KANG; Oh-Sang KWON; Yong-Kyoo SHIN; Jin-Ho SONG; Moo-Yeol LEE; Kwang-Gill LEE; Joo-Hong YEO; Won-Bok LEE; Tae-Jin LEE; Sung-Su KIM; Sang-Hyung LEE; Yong-Sik KIM; Yong-Koo KANG; Oh-Sang KWON; Yong-Kyoo SHIN; Jin-Ho SONG; Moo-Yeol LEE; Kwang-Gill LEE; Joo-Hong YEO; Won-Bok LEE; Tae-Jin LEE; Sung-Su KIM; Sang-Hyung LEE; Yong-Sik KIM; Yong-Koo KANG; Oh-Sang KWON; Yong-Kyoo SHIN; Jin-Ho SONG; Moo-Yeol LEE; Kwang-Gill LEE; Joo-Hong YEO; Won-Bok LEE; Tae-Jin LEE; Sung-Su KIM; Sang-Hyung LEE; Yong-Sik KIM; Yong-Koo KANG; Oh-Sang KWON; Yong-Kyoo SHIN; Jin-Ho SONG; Moo-Yeol LEE; Kwang-Gill LEE; Joo-Hong YEO; Won-Bok LEE; Tae-Jin LEE; Sung-Su KIM.
The Korean Journal of Physiology and Pharmacology
; : 307-312, 2004.
Artículo
en Inglés
| WPRIM | ID: wpr-727784
To investigate whether BF-7, extracted from Bombyx mori, improved learning and memory of ordinary people, Rey-Kim Memory Test was performed with placebo group (32 persons), 200 mg BF-7 treated group (33 persons) and 400 mg BF-7 treated group (34 persons). BF-7 enhanced significantly learning and memory function in a dose-dependent manner. To know how BF-7 plays such a positive role, we measured the concentration of acetylcholine in the brain from memory impairment animal model. Treatment of BF-7 significantly increased the concentration of acetylcholine. So, it is supposed that the protection of cholinergic neuron and/or keeping proper concentration of acetylcholine might be one of the mechanisms by which BF-7 improve brain function. So, our results suggest that the BF-7 is effective material for improving learning and memory ability.
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