Repetitive transcranial magnetic stimulation for post-stroke dysphagia: A meta-analysis
Bernardo-Aliling Nicole A; Rivera Adovich S; Pasco-Paul-Matthew-D; Nicole A. Bernardo-Aliling; Adovich S. Rivera; Paul-Matthew D. Pasco.
Acta Medica Philippina
; : 327-333, 2017.
Artículo
en Inglés
| WPRIM | ID: wpr-732122
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BACKGROUND:
</strong> Dysphagia is common among post-stroke patients,causing disability due to malnutrition and pneumonia. Repetitive transcranial magnetic stimulation (rTMS) is a novel treatment modality to address this complication.</p><p style="text-align justify;"><strong>OBJECTIVE:
</strong> The study aimed to compare real versus sham rTMS in treating post-stroke dysphagia.</p><p style="text-align justify;"><strong>METHODS:
</strong> PubMed, Ovid, ClinicalKey, Herdin, and Google Scholar databases were searched from their earliest record to 31 July 2015 for randomized controlled trials that used rTMS to treat post-stroke dysphagia. The Jadad scale was used to assess the quality of the studies. The weighted mean difference (WMD) between baseline and post-treatment mean for Penetration Aspiration Scores (PAS) measured in the experimental and control groups were extracted for subsequent meta-analyses.</p><p style="text-align justify;"><strong>RESULTS:
</strong> Three studies were analyzed. The WMD in PAS score between rTMS and control using liquid bolus two weeks after treatment in two good quality studies was -1.14 (95% confidence interval (CI) = -1.80 - -0.48, P = 0.001, I2 = 0.0%), and after four weeks was -1.83 (CI = -3.22 - -0.44, P = 0.010, I2 = 0.0%).</p><p style="text-align justify;"><strong>CONCLUSION:
</strong> Treatment of post-stroke dysphagia with rTMS improved PAS on subgroup analyses of studies using liquid bolus after two weeks, and between real and sham treatment after four weeks.?</p>
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