A Case of Clozapine-induced Corneal and Lenticular Pigmentation
Ji-Seon AN; Young-Mi LEE; Joo-Young KWAG; Joo HYUN; Jin-Seok CHOI; Kyu-Hong PAK; Sung-Kun CHUNG.
Journal of the Korean Ophthalmological Society
; : 276-279, 2019.
Artículo
en Ko
| WPRIM | ID: wpr-738608
PURPOSE:
To report a case of corneal and lenticular pigmentation after prolonged clozapine therapy. CASESUMMARY:
A 56-year-old male visited our hospital with a progressive decline in vision that affected both eyes. He had a history of schizophrenia. He was being treated with 200 mg clozapine and 1 mg lorazepam daily, and had been treated with clozapine for 5 years. At the first visit, his best-corrected-visual acuity was 20/32 in both eyes. Slit lamp examination of the corneas showed bright, fine, grayish-brown deposits on the endothelium, and on dilation, bilateral central stellate opacity of the anterior portion of the lens capsule was revealed.CONCLUSIONS:
Clozapine may induce corneal and lenticular pigmentation and thus may lead to a decline in vision. Patients on long-term clozapine therapy should be considered for regular ophthalmic review.
Biblioteca responsable:
WPRO
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