Ganglioneuroma of the
gastrointestinal tract is a rare
tumor that consists of
ganglion cells, nerve fibers, and supporting
cells of the
enteric nervous system.
Ganglioneuromas are usually associated with
genetic disorders such as the
multiple endocrine neoplasia syndrome or
neurofibromatosis.
Ganglioneuromas of the
gastrointestinal tract predominantly involve the
colon and
rectum, and
reports about duodenal
ganglioneuromas are few. Herein, we
report a case of duodenal
ganglioneuroma treated with endoscopic resection. A 56-year-old
female patient visited our
hospital because of a subepithelial
tumor in the second portion of the
duodenum. She had no remarkable medical or
family history and revealed no
history of
genetic disorders.
Endoscopic ultrasonography and abdominal computed
tomography revealed a
tumor located mainly in the submucosal layer, without any regional
lymph node involvement. Endoscopic resection of the lesion was performed, and the pathological examination confirmed a duodenal
ganglioneuroma.