A Case of Lactic Acidosis Caused by Linezolid Treatment of Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia / 대한내과학회지
Yu-Seok KIM; Ji-Beom KIM; Yumi LEE; Sung-Han KIM; Sang-Ho CHOI; Jun-Hee WOO; Yang-Soo KIM; Yu-Seok KIM; Ji-Beom KIM; Yumi LEE; Sung-Han KIM; Sang-Ho CHOI; Jun-Hee WOO; Yang-Soo KIM.
Korean Journal of Medicine
; : 512-515, 2012.
Artículo
en Ko
| WPRIM | ID: wpr-741080
Linezolid is an antibiotic in the oxazolidinone family that works as a bacterial protein synthesis inhibitor. It is used for the treatment of Gram-positive, multidrug-resistant bacteria. Adverse effects of linezolid include bone marrow suppression, peripheral or optic neuropathy, and, less commonly, lactic acidosis. Lactic acidosis usually occurs as a result of cardiopulmonary failure or sepsis, but it is sometimes caused by drugs, such as linezolid, and treatment of such lactic acidosis involves cessation of the drug. We report a case of lactic acidosis caused by the use of linezolid for the treatment of persistent methicillin-resistant Staphylococcus aureus bacteremia, which occurred after endoscopic sclerotherapy of gastic varices.
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