@#Objective To analyze the
risk factors of the
death associated with
infective endocarditis, and to evaluate the timing of surgical
treatment of
infective endocarditis.
Methods We retrospectively analyzed the clinical data of 62
patients with
infective endocarditis in our
hospital between August 2015 and August 2017. There were 43
males and 19
females at age of 19–75 (46.1±16.6) years. The clinical data were divided into a
death group and a
survival group, a paravalvular
leakage group and a no periannular
leakage group, an
emergency operation group and a non-
emergency operation group.The
risk factors of
infective endocarditis and the choice of operation
time were analyzed. Results Three of the 62
patients (4.8%) died after
surgery. Postoperative perivalvular
leakage (regurgitation over 2 mm) in 8
patients,
accounting for 12.9% of the total. Univariate
analysis showed that
albumin content,
creatinine level, total
cardiopulmonary bypass time and
ascending aorta occlusion
time were significantly associated with early postoperative
mortality (P<0.05). The results of logistic
analysis showed that age, preoperative
albumin level,
creatinine level, total
cardiopulmonary bypass time, and
ascending aorta occlusion
time were significantly associated with early postoperative perivascular
leakage (P<0.05), and long
ascending aorta occlusion
time is an independent
risk factor for early
death (P<0.05). There was no statistical difference in early
death and the perivalve
leakage between the
emergency operation and the non
emergency operation. Conclusion
Patients with
infective endocarditis should accept early surgical
treatment. The choice of surgical approach should be selected according to the actual situation of
patients. And we should pay more
attention to
albumin and
creatinine levels in preoperative
patients. In the operation, to shorten
extracorporeal circulation time and aortic
clamping time can improve the
prognosis of
patients.