Objective To analyze the independent
risk factors for hemorrhagic transformation (HT)after endovascular mechanical
thrombectomy in
patients with
acute ischemic stroke (AIS).
Methods From March 2015 to February 2018,
patients with AIS treated with mechanical
thrombectomy at the Department of
Neurology,TEDA
Hospital were selected.The
patients with hemorrhagic
infarction (HI) or parenchymal
hematoma (
PH) were used as the case group,and those without HT were used as the
control group.The independent
risk factors for HI or
PH after mechanical
thrombectomy in
patients with AIS were determined by multivariate
logistic regression analysis.Results A total of 132
patients with AIS were enrolled in the study,and 60 (45.4%) developed HT,of which 37 were HI (28.03%) and 23 were
PH (17.42%).Multivariate
logistic regression analysis showed that after adjusting for
gender,
alcohol consumption,
fasting blood glucose and
glycated hemoglobin,diabetes (
odds ratio [OR] 3.485,95%
confidence interval[CI]l.121-6.928;P=0.019),
atrial fibrillation (OR 3.962,95% CI 1.143-7.514;P =0.007) and high
fasting blood glucose (OR 3.254,95% CI 1.107-6.549;P =0.036) were the independent
risk factors for HI after mechanical
thrombectomy in
patients with AIS;after adjusting for
gender,
hyperlipidemia and
glycosylated hemoglobin,diabetes (OR 3.348,95% CI 1.120-6.709;P =0.025) and high
fasting blood glucose (OR 3.172,95% CI 1.129-7.023;P =0.014) were the independent
risk factors for
PH after mechanical
thrombectomy in
patients with AIS.Conclusion Diabetes,
atrial fibrillation and high
fasting blood glucose were the independent
risk factors for HT after mechanical
thrombectomy in
patients with AIS.