@#Objective To investigate the effect of artificial
colloid on coagulation function in pediatric
patients weighing less than 5 kg with
congenital heart disease during
cardiopulmonary bypass in
congenital heart disease surgery by using artificial
colloid instead of
human serum albumin .
Methods A total of 65 pediatric
patients with weight less than 5 kg
who underwent
congenital heart disease surgery in our
hospital from September 2016 to December 2017 were included in the study. They were randomly divided into two groups an artificial
colloid group (the experimental group, n=33) and a
human serum albumin combined artificial
colloid group (the
control group , n=32). Perioperative
hemoglobin concentration (Hb),
blood products and
hemostatic drugs used, postoperative coagulation function index and pleural fluid volume 24 hours after
surgery were monitored. Results There was no significant difference in perioperative Hb and
chest tube drainage between the two groups. The
platelet utilization rate in the experimental group was significantly lower than that in the
control group (P<0.05). No significant difference was found in the
dosage of other
blood products and
hemostatic drugs between the two groups during the
perioperative period . There was no significant difference in coagulation
parameters between the two groups before and after
surgery (P>0.05). Conclusion The use of artificial
colloid as
colloid priming
solution during
cardiopulmonary bypass has no adverse effect on coagulation function in pediatric
patients weighting less than 5 kg with
congenital heart disease .