The Influence of Atopic Findings on Severity of Pneumonia in Children with 2009 Pandemic Influenza A (H1N1) Infection / 소아감염
Jong-Hee KIM; Hyun-Jeong KIM; Im-Ju KANG.
Korean Journal of Pediatric Infectious Diseases
; : 182-192, 2011.
Artículo
en Ko
| WPRIM | ID: wpr-75117
PURPOSE:
Atopic findings may be associated with severity of pneumonia in 2009 pandemic influenza A (H1N1) infection, which could suggest a possible association between atopic findings and the severity of viral infections. Thus, we studied association between atopic findings and severity of disease in children with H1N1 influenza infection.METHODS:
A retrospective study was performed in 74 children admitted in a single tertiary institute and confirmed as H1N1 patients by reverse transcriptase (RT) - polymerase chain reaction (PCR). They were divided into 2 groups according to the severity of pneumonia. We evaluated whether the atopic finding is risk factor between the two groups.RESULTS:
Children with severe pneumonia had higher percentages of serum eosinophilia (88% vs 40%, P<0.001), asthma (65% vs 35%, P=0.011), allergic rhinitis (71% vs 40%, P=0.009), and IgE level (P=0.007). We found positive correlations between aeroallergen sensitizations and severity of pneumonia (82% vs 53%, P=0.007).CONCLUSION:
Among patients with H1N1 pneumonia, asthma and atopic findings are risk factors for severity of pneumonia.
Biblioteca responsable:
WPRO
Texto completo
Documentos relacionados