Study on sesquiterpenes from agarwood originating from Gyrinops salicifolia / 中国中药杂志
Hui-Qin CHEN; Feng-Juan GUO; Cai-Hong CAI; Wen-Hua DONG; Hao WANG; Wei LI; Wen-Li MEI; Hao-Fu DAI.
China Journal of Chinese Materia Medica
; (24): 2274-2277, 2019.
Artículo
en Zh
| WPRIM | ID: wpr-773097
Two sesquiterpenes were isolated from the agarwood originating from Gyrinops salicifolia with various chromatographic techniques, and their structures were determined as 12-hydroxy-dihydrocyperolone(1) and(rel)-4β,5β,7β-eremophil-9-en-12,8α-olide(2), through a combined analysis of physicochemical properties and spectroscopic evidence. Compound 1 was a new compound. Compound 2 showed cytotoxicities against K562 and BEL-7401 cell lines, with IC_(50) values of(17.85±0.04) and(21.82±0.07) mg·L~(-1), respectively [taxol as positive control, with IC_(50) values of(1.97±0.11) and(6.31±0.08) mg·L~(-1)].
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