Liver cirrhosis is the final outcome of various chronic
liver diseases. In recent years, along with the rapid development of
molecular biology and
cell biological engineering technology,
liver regeneration based on
stem cell transplantation technique has become a new
research hotspot for
treatment of acute and chronic
hepatic failure. Here we
review basic and clinical studies on different types of
stem cells for the
treatment of
liver cirrhosis and optimal choices of the
stem cell type used for
transplantation based on
specificity of
patients' particular status. A large number of experimental studies reveal that the
technology of
stem cell for the
treatment of
liver cirrhosis has gradually become mature with a broad prospect of application in the field of
liver regeneration. This
technology that holds enormous potential for
treatment will bring
hopes to the
patients with end-stage
liver cirrhosis.