Leiomyosarcoma is a
malignant neoplasm of
smooth muscle origin and mostly originate from the wall of
uterus and
gastrointestinal tract, but primary
leiomyosarcoma of the
oral cavity is extremely rare. This
tumor has a very poor
prognosis due to high
recurrence and
metastasis rate, with 5 year
survival rate of 32%. And regional
lymph node metastasis is uncommon event. Complete wide surgical excision is the
treatment of choice.A 64-year old man
who had a painful ulcerative lesion on the labial & palatal
gingiva of #11, 21 visited our department, and was diagnosed as
leiomyosarcoma through a
biopsy. Partial maxillectomy was carried out, with no following
radiotherapy or
chemotherapy. After months follow-up, there has been no evidence of
recurrence or
metastasis. But after months, we clinically find out two enlarged immobile palpable
lymph node in right submandibular area of
patient. So a
biopsy was performed via an extraoral incision under
local anesthesia. Histopathologic
diagnosis diagnosis of the
biopsy was
lymph node metastasis of prior existed
leiomyosarcoma. We
report a case of a primary
leiomyosarcoma occurred in a 64 year-old
male patient involving the anterior maxillary region with regional
lymph node metastasis with a
review of
literature.