Objective@#To make a preliminery
research of comobidity in
oral squamous cell carcinoma (OSCC)
patients who resides in
Beijing area and investigate whether
comorbidity affect the surviving rate independently. Compare the similarities and differences between
Chinese and foreign OSCC
patients.@*
Methods@#The
medical records of 313
patients who undertaken operation in
Peking University Stomatology School from January 2007 to Delember 2009 were retrospectively reviewed.
Adult comorbidity evaluation-27
Chinese edition index was used to estimate the
comorbidity severity.
COX proportional hazards model was used to analyze whether the TNM stage, comobidity, age and
gender affected 5-year
survival rate.@*Results@#TNM stage and
comorbidity have a significant impact on
survival rate, the postoperative
survival rate decreased significantly with the increasing level of
TNM staging and the complexity of
comorbidity disease. In this study, the proportion of
patients with none, mild, moderate and severe
comorbidity diseases was 24%, 48%, 18% and 10%. The five-year
survival rates of
patients with moderate and severe
comorbidity disease were 50% (29/58) and 13% (4/30) respectively.@*Conclusions@#The
comorbidity disease information can help assess the
overall health of OSCC
patients, and it is recommended to improve the clinical staging and overall evaluation of
oral cancer patients with
comorbidity disease information.