Two new phragmalin-type limonoids orthoesters from Entandrophragma candollei / 中国天然药物
Olga QUASIE; Hui LI; Jun LUO; Ling-Yi KONG.
Chinese Journal of Natural Medicines (English Ed.)
; (6): 680-683, 2017.
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| WPRIM | ID: wpr-812068
Two new phragmalin-type limonoids orthoesters, encandollens A and B (1 and 2), were isolated from the stem barks of Entandrophragma candollei collected in Ghana. The structures of these compounds were elucidated on the basis of HR-ESI-MS, H and C NMR, HSQC, HMBC, and ROESY data. Compound 1 was a rare C-15 enolic acyl phragmalin-type limonoid orthoester. Compounds 1 and 2 exhibited weak inhibitory effects on NO production in lipopolysaccharide (LPS)-induced RAW 264.7 cells.
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