From July 2013 to February 2015, 4
infant patients with complex
congenital heart disease,
who underwent open
heart surgery in Xiangya
Hospital of Central South
University, were diagnosed as
heparin-induced
thrombocytopenia (HIT). After comprehensive
treatments, such as intensive
monitoring of the
platelet count, close
observation of thromboembolic
skin lesions and close
monitoring of argatroban
therapy, 3
patients were cured and 1 died. HIT is rare but serious in
patients who received
heparin therapy. The
incidence of
mortality and
thrombosis is very high. Early identification and
diagnosis of high-
risk groups can improve the
prognosis.