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Genotypic characterization of fluoroquinolone-resistant Escherichia coli isolates from edible offal

Se-Hyun SON; Kwang-Won SEO; Yeong-Bin KIM; Eun-Bi NOH; Keun-Woo LEE; Tae-Ho OH; Seung-Joon KIM; Jae-Chan SONG; Tae-Wan KIM; Young-Ju LEE.
Artículo | WPRIM | ID: wpr-836809
Abstract Edible offal is easily contaminated by Escherichia coli (E. coli) and fluoroquinolone (FQ)-resistant E. coli is considered a serious public health problem, thus, this study investigated the genetic characteristics of FQ-resistant E. coli from edible offal. A total of 22 FQ-resistant E. coli isolates were tested. A double mutation in each gyrA and parC led the highest MIC. Four (18.2%) isolates carried plasmid-mediated quinolone resistance genes. The fimH, eaeA, escV, astA, and iucC genes were confirmed. Seventeen isolates (77.3%) were positive for plasmid replicons. The isolates showed high genetic heterogeneity based on pulsed-field gel electrophoresis patterns.
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