Objective • To evaluate the
recurrence rate of
atrial fibrillation (Af) and its related
risk factors in
aged patients with
chronic diseases after cryoballoon ablation.
Methods • With the
method of convenient sampling, a total of 159
patients with Af after cryoballoon ablation were enrolled in the Department of
Cardiology, Ruijin
Hospital from Oct. 2016 to Jan. 2018.
Self-rating
depression scale (SDS) and CHA2DS2-VASc scores [
congestive heart failure,
hypertension, age ≥ 75 y (doubled),
diabetes mellitus,
stroke(doubled)-
vascular disease, age 65-74 and
sex category(
female)] were used to assess the
patients. Follow-up checks consisted of chief complaint, postoperative
electrocardiogram (
ECG), and 24 h
Holter monitoring.
Logistic regression models were performed to explore the independent
risk factors of Af
recurrence after cryoballoon ablation. Results • 152
patients (95.6%) completed the follow-up checks, with an average age of (61.9±8.9) years. The average
time of follow-up period was (8.35±2.41) months. A total of 41
patients (27.0%) developed Af after cryoballoon ablation.
Logistic regression analysis showed the number of
chronic disease ≥ 2 (OR=2.466, 95% CI 1.375-4.452), CHA2DS2-VASc scores ≥ 2 (OR=2.088, 95% CI 1.142-5.557), irregular use of
anti-arrhythmic drugs (OR=1.581, 95% CI 1.351-2.125),
hypertension (OR=1.317, 95% CI 1.076-2.809), and
body mass index (BMI) (OR=1.147, 95% CI 1.009-1.174) were the independent
risk factors of Af
recurrence. Conclusion • There is still a certain percentage of
recurrence in
aged patients with
chronic diseases after cryoballoon ablation. 2 and more
chronic diseases, irregular use of
anti-arrhythmic drugs,
hypertension, CHA2DS2-VASc scores ≥ 2, and
overweight may be potential
risk factors of Af
recurrence after cryoballoon ablation.