Peripheral T-cell lymphomas (PTCLs) are a group of heterogeneous
diseases originating from post-thymic
T-cells, with poor
prognosis using traditional
therapy, especially in
patients with relapsed/refractory PTCLs (r/rPTCLs). In recent years, a variety of new anti-
tumor drugs have emerged in the
treatment of r/rPTCLs, including different types of
enzyme inhibitors,
monoclonal antibodies,
immunomodulators and
immune checkpoint inhibitors, which have been proved to be effective. The discovery and clinical application of
new drugs are expected to improve the outcomes of the
diseases.