Changes and significance of soluble low-density lipoprotein receptor-related protein-1 and regulated upon activation normal T cell expressed and secreted in acute coronary syndrome / 中国综合临床
The plasma levels of lg sLRP-1 and RANTES in AMI group ((0.69±0.20) mg/L and(125.17±34.87 )ng/L) and UAP group ((0.62±0.19) mg/L and(118.51±21.46 ) ng/L) were higher than SAP group ((0.42±0.16) mg/L and(99.56±21.46)ng/L) and control group ((0.27±0.08) mg/L and (98.39±19.37)ng/L)(all P<0.05), while lg sLRP-1 and RNATES levels were not significantly different between AMI group and UAP group, SAP group and control group(all P>0.05). The levels of lg sLRP-1 and RANTES in patients with ACS decreased after PCI treatment(all P<0.05). Plasma lg sLRP-1 and RANTES levels were not correlated with Gensini scores in ACS patients(all P>0.05).
Conclusion:
SLRP-1 and RANTES are involved in the progression of ACS, and there is a certain correlation between them.Myocardial perfusiontherapy improves the inflammatory response of coronary artery.