To observe the short-term intraocular pressure changes of the affected eye after the implantation of dexamethasone vitreous implant (Ozurdex), and indirectly understand the tightness of the scleral perforation of the 22G implant device.
The average baseline intraocular pressure of the affected eye was 14.85 [interquartile range (IQR) 11.60, 17.63] mmHg (1 mmHg=0.133 kPa). The average intraocular pressureat 10, 30 and 2, 24 hours after implantation were 11.90 (IQR 8.95, 16.30), 13.75 (IQR 9.95, 16.80), 13.60 (IQR 10.95, 17.20), and 14.65 (IQR 12.20, 17.50) mmHg. Compared with the baseline intraocular pressure, the intraocular pressure decreased at 10 and 30 minutes after implantation, the difference was statistically significant ( P<0.001, P=0.002); the intraocular pressure difference was not statistically significant at 2, 24 h after implantation ( P=0.140, 0.280).
Conclusions:
There is a statistically significant difference in intraocular pressure reduction compared with the baseline in 10 and 30 minutes after vitreous implantation of Ozurdex, and there is no statistically significant difference between 2, 24 hours. This suggests that the 22G scleral puncture port of the preinstalled implant device cannot be completely closed immediately, and short-term intraocular pressuremonitoring after implantation should be appropriately strengthened.