Objective:
To observe the
clinical efficacy of Jiwei Huangqi Guizhi Wuwutang combined with Xingnao Kaiqiao
acupuncture on shouder-
hand syndrome (SHS), and its effect on neurogenic inflammatory factors and
hemorheology.
Method:
One hundred and forty-eight
patients were randomly divided into
control group and
observation group (74 cases). Both groups'
patients got
rehabilitation measures, such as
diclofenac sodium sustained release
tablets for two to four weeks, 75 min/
time, 1
time/day, and
patients with apparent swelling got
prednisone acetate tablets for one to two weeks, 10 min/
time, 1
time/day. And
patients in
control group got Xingnao Kaiqiao
acupuncture, 1
time/day, 6 times/week. Control grouporal Naoxintong
capsule 4
tablets/
time,3 times/day,
patients in
observation group were added with Jiwei Huangqi Guizhi Wuwutang, 1
dose/day. The
courses of
treatment were 4 weeks. Before and
after treatment,
shoulder hand syndrome scale (SHSS), the upperextremities of the Fugl-meyer
movement assessment (U-FMA),
ability of daily
life activities (
ADL),
Qi deficiency and
blood stasis
syndrome and
clinical efficacy were scored, disappearing
time of
pain and swelling were recorded, and levels of
calcitonin gene related peptide (CGRP),
substance P (SP),
bradykinin (BK) and
hemorheology were detected.
Result:
The
clinical efficacy in
observation group was better than that in
control group (Z=2.106, P<0.05). And scores of sensory, autonomic,
motion according to SHSS scale and the total scale of SHSS were all lower than those in
control group (P<0.01). Disappearing
time of
pain and swelling were shorten than those in
control group (P<0.01).
After treatment, scores of U-FMA and
ADL were higher than those in
control group (P<0.01), while score of
syndrome of
Qi deficiency and
blood stasis was lower than that in
control group (P<0.01). And level CGRP was higher than that in
control group (P<0.01), and levels of SP and BK were lower than those in
control group (P<0.01).
After treatment, whole
blood viscosity (high cut, low cut),
plasma viscosity,
fibrinogen and
platelet aggregation rate were all lower than those in
control group (P<0.05).
Conclusion:
In addition to the conventional western
medicine therapy, Jiwei Huangqi Guizhi Wuwutang combined with Xingnao Kaiqiao
acupuncture can reduce the severity of SHS and clinical
syndromes of
traditional Chinese medicine, shorten the
course of
disease, improve the motor function of
upper limbs, inhibit the neurogenic inflammatory reaction, and improve the
blood flow, the
ability of daily
life and the
clinical efficacy of
patients..