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A new cadinane-type sesquiterpenoid from Commiphora myrrha / 药学学报

Chao-chao WANG; Hui XIA; Nai-yun LIANG; Rong-ye WANG; Xin-yu WANG; Hui-na YAO; Hui-xia HUO; Peng-fei TU; Jun LI.
Acta Pharmaceutica Sinica ; (12): 831-834, 2021.
Artículo en Zh | WPRIM | ID: wpr-876526
Five cadinane-type sesquiterpenoids were isolated from the n-hexane extract of Commiphora myrrha by using various chromatographic techniques, including silica gel, ODS and semi-preparative HPLC. Their structures were identified by physicochemical properties and spectroscopic data. These compounds were defined as (3S,4R)-3,9-dimethoxymyrrhone (1), 9-methoxymyrrhone (2), myrrhone (3), commiterpene B (4) and comosone Ⅱ (5). Compound 1 is a new compound, of which the absolute configuration was established by single crystal X-ray crystallographic analysis. Compound 5 is firstly isolated from the Commiphora genus.
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