OBJECTIVE@#To compare the
therapeutic effect on
type 2 diabetes mellitus (T2DM) complicated with
angina pectoris of
coronary heart disease between the combined
therapy of
acupuncture and western medication and the simple
administration of western medication.@*
METHODS @#A total of 134
patients with T2DM and
angina pectoris of
coronary heart disease were randomly divided into two groups, i.e. an
acupuncture plus medication group (67 cases, 3 cases dropped off) and a medication group (67 cases, 4 cases dropped off). The routine western medication was used according to symptoms in the
patients of both groups. In the
acupuncture plus medication group, on the base of medication,
acupuncture was applied to Jianshi (PC 5), Quchi (LI 11), Neiguan (PC 6), etc. The
needles were retained for 20 min in each
treatment and 3
treatments of
acupuncture were required weekly. The
treatment was given consecutively for 8 weeks in the two groups. Separately, before and
after treatment , the symptom scores of TCM were observed and the indexes were detected, including
glycolipid metabolism [
fasting plasma glucose (FPG), 2-h
plasma glucose (2hPG), glucosylated
hemoglobin (HbA1c),
triacylglycerol (TG) and total
cholesterol (TC)], islet β
cell function [
homeostasis model assessment-β (HOMA-β),
homeostasis model assessment-IR (HOMA-IR),
fasting insulin (FINS) and
insulin sensitivity index (ISI)], cardiac function indexes [
cardiac output (CO), early diastolic peak velocity/late diastolic peak velocity (E/A), left ventricular end diastolic diameter (LVEDD) and left
ventricular ejection fraction (LVEF)], as well as
electrocardiogram QT dispersion (QTd). Besides, the clinical
therapeutic effects were compared between the two groups.@*RESULTS@#
After treatment , the TCM symptom scores and the values of FPG, 2hPG, HbA1c, TG, TC, HOMA-IR, FINS, E/A and LVEDD as well as QTd were all lower than those before
treatment in the two groups (@*CONCLUSION@#The combined
therapy of
acupuncture and medication is effective in
treatment of T2DM complicated with
angina pectoris of
coronary heart disease . Such
therapy effectively improves glucolipid
metabolism , islet β
cell function, cardiac function and myocardial
blood supply . Its curative effect is better than the simple
administration of western
medicine .