Objectives: To analyze the clinical characteristics of
patients undergoing extracorporeal
cardiopulmonary resuscitation (ECPR) and identify the
risk factors for
death .
Methods: The clinical data of 60
patients undergoing ECPR admitted to our
hospital and Hangzhou First People's
Hospital from September 2014 to September 2019 were retrospectively analyzed. The
patients were divided into the
survival group and the
death group. The clinical data of the two groups were compared to explore the
risk factors related to
death . COX
regression analysis was used to identify the
risk factors for
death .
Results: Sixty
patients undergoing ECPR were included in our study, of them, 16 (26.7%) cases were
out-of-hospital cardiac arrest (OHCA) and 44 (73.3%) cases were in-
hospital cardiac arrest (IHCA). The
mortality of OHCA
patients was higher than that of IHCA
patients (87.5% vs. 56.89%, P < 0.05), and the duration from
CPR to ECMO installation in the
death group was longer than that in the
survival group [(105.4±105.1) min vs. (53.0±28.5) min, P < 0.05]. Compared with the
survival group,
patients in the
death group had higher
troponin and glutamic oxalacetic
transaminase and lower
PH and
lactate ( P < 0.05). The median
survival time of the 60
patients was 42 days.
Out-of-hospital cardiac arrest , high SOFA score before ECMO, high-
dose norepinephrine , pulmonary
infection during ECMO support and long ECMO support
time were independent predictors of
patients ’
death .
Conclusions: Risk factors associated with
patients ’
death undergoing ECPR are
out-of-hospital cardiac arrest , high SOFA score before ECMO, high-
dose norepinephrine , long duration from
CPR to ECMO installation, pulmonary
infection during ECMO support and long ECMO support
time .