Objective To observe the effect of
tiopronin combined with
glutathione on the levels of
alanine aminotransferase (ALT),
aspartate aminotransferase (AST), glutamyltransferase (GGT),
blood fat and
laminin (LN) in
patients with non-
alcoholic fatty liver.
Methods A total of 84 non-
alcoholic fatty liver patients admitted to our
hospital from March 2018 to September 2019 were selected and randomly divided into
control group and
observation group, with 42 cases in each group. The
control group was treated with
tiopronin, and the
observation group was treated with
glutathione and
tiopronin. The levels of ALT, AST, GGT and
blood fat were recorded and compared before and
after treatment. Results
After treatment, the levels of ALT, AST and GGT in the two groups were significantly lower than before
treatment (P<0.05).
After treatment, the levels of ALT, AST, and GGT in the
observation group were different from those in the
control group, which was statistically significant (P<0.05). Before
treatment, there was no difference in
serum TC, TG, and LDL levels between the two groups, which was not statistically significant (P>0.05). The above-mentioned
serum levels of the
observation group
after treatment were lower than those in the
control group, and there was a difference, which was statistically significant (P<0.05); the levels of PCⅢ, PCⅣ, and LN in the
treatment group
after treatment were significantly lower than those of the
control group. The difference was statistically significant (P<0.05). Conclusion The application of
tiopronin combined with
glutathione in the
treatment of non-
alcoholic fatty liver can promote the recovery of
liver function and reduce the concentrations of TC, TG and LDL, which is worthy of clinical promotion.