Astragalus membranaceus has the effect of tonifying
Qi and solid surface,
diuretic support
poison, discharging
pus and
astringent sores to produce
muscle. It is not only used for
syndromes such as
deficiency of
lung and temper,
deficiency of
spleen and
diarrhea, but also for
stroke,
chest obstruction and other
diseases. Due to the complex chemical composition and diverse pharmacological effect of
Astragalus membranaceus, and the main
role in invigorating
qi and activating
blood circulation has not been clarified. Astragaloside Ⅳ is one of its main active ingredients. In recent years, more and more studies on Astragaloside Ⅳ have been conducted at home and abroad. It has been reported that it has the medicinal value of enhancing immune function, strengthening
heart and lowerin
blood glucose,
diuresis, anti-
aging and anti-
fatigue, et al, and has extensive pharmacological activity. Among them, the
role of cardiovascular and
cerebrovascular diseases in particular has attracted increasing
attention. Cardiovascular and
cerebrovascular diseases are ischemic or hemorrhagic
diseases occurring in the
heart,
brain and systemic
tissues due to
blood viscosity,
atherosclerosis,
hypertension,
hyperlipidemia, etc., including cardiovascular and
cerebrovascular diseases. Such
diseases are a serious threat to mankind and are the leading
cause of death worldwide. At present, western
medicine is the main
treatment, with many adverse reactions and poor long-term
prognosis. TCM believes that the imbalance of
qi and
blood is the basic pathogenesis of this kind of
disease.
Qi deficiency and
blood stasis are more common.At present, Astragaloside Ⅳ in the
treatment of cardiovascular and
cerebrovascular diseases in a number of studies, and achieved some results, but this
review in recent years, Astragaloside Ⅳ in the
treatment of cardiovascular and
cerebrovascular diseases play the pharmacological activity, in order to explore whether Astragaloside Ⅳ is the main
role of astragalus
qi to find a theoretical basis for material basis, but also for the innovation of
traditional Chinese medicine drug research and development of theoretical basis and practical guidance.