A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children
So-Yeon LEE; Kangmo AHN; Jihyun KIM; Gwang-Cheon JANG; Taek-Ki MIN; Hyeon-Jong YANG; Bok-Yang PYUN; Ji-Won KWON; Myung-Hyun SOHN; Kyung-Won KIM; Kyu-Earn KIM; Jinho YU; Soo-Jong HONG; Jung-Hyun KWON; Sung-Won KIM; Tae-Won SONG; Woo-Kyung KIM; Hyung-Young KIM; You-Hoon JEON; Yong-Ju LEE; Hae-Ran LEE; Hye-Young KIM; Youngmin AHN; Hye-Yung YUM; Dong-In SUH; Hyun-Hee KIM; Jin-Tack KIM; Jeong-Hee KIM; Yong-Mean PARK; Sooyoung LEE.
Allergy, Asthma & Immunology Research
; : 535-540, 2016.
Artículo
en Inglés
| WPRIM | ID: wpr-90954
PURPOSE:
Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children.METHODS:
We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea.RESULTS:
A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes.CONCLUSIONS:
The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.
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