Objective:
We aimed to estimate the
incidence of
anxiety or
depression in
asthma-
chronic obstructive pulmonary disease (
COPD) overlap (ACO)
patients and explore its related factors.
Methods:
Stable
patients who were treated or followed up in the
outpatient department of
respiratory medicine in the First
Hospital of
China Medical
University from March 2018 to March 2019 were enrolled, including 53 ACO
patients, 74
asthma patients, and 138
patients with
COPD. Hamilton
Depression Scale (HAMD) and Hamilton
Anxiety Scale (HAMA) were used to evaluating the
anxiety and
depression status of the three groups of
patients, and the
risk factors of
anxiety and/or
depression in ACO
patients were analyzed.
Results:
There were 33 cases (62.3%), 35 cases (47.3%) and 69 cases (50.0%) combined with
anxiety in ACO,
asthma and
COPD group; there were 29 cases (54.7%), 25 cases (33.8%) and 58 cases (42.0%) combined with
depression in ACO,
asthma and
COPD group, respectively. The
patients with
depression in ACO were significantly higher than those in
asthma group ( P<0.05). There were 28
patients (52.8%), 24
patients (32.4%) and 52
patients (37.7%) combined with
anxiety and
depression in ACO,
asthma and
COPD group, respectively, with significant difference in ACO group and
asthma group ( P<0.05). Multivariate
logistic regression analysis showed that
chronic obstructive pulmonary disease assessment test (
CAT) score≥10 was associated with
anxiety ( OR=15.00, P<0.01) or
depression ( OR=8.667, P<0.01) in
patients with ACO.
Conclusions:
Anxiety/
depression is common in chronic
airway disease. Compared with
asthma,
anxiety and/or
depression is more frequent in the
patients with ACO. ACO
patients with high
CAT scores should pay
attention to
screening for
anxiety/
depression.