Objective: To analyze the impact of rare
bacteria infection on clinical outcome in
patients with
diabetic foot ulcer (DFU).
Methods: A total of 288 cases infected with single
strains bacteria were selected. Data were grouped according to the 15
bacteria infection identified. The outcomes of healing,
amputation , cardio and cerebrovascular events, and
death were collected, and
risk factors to the outcome were analyzed.
Results: The rare infected
bacteria were
acinetobacter baumannii ,
staphylococcus epidermidis , morgan
morganella ,
staphylococcus haemolyticus ,
streptococcus lactis ,
streptococcus agalactiae ,
enterobacter cloacae , and
serratia marcescens .There were significant differences in age,
albumin , HbA 1C,
body mass index , condition of
foot ulcer , degree of
infection , healing, and
minor amputation among these groups. Severe
lower extremity arterial
disease and age over 70 years were the main
risk factors for the healing of
ulcers . Wagner grade over 3 and infected with
streptococcus lactis were the main
risk factors for
minor amputation . Severe
lower extremity arterial
disease ,
hemoglobin (Hb)≤90 g/L, and
albumin (ALB)≤30 g/L were the main
risk factors for major
amputation . Estimated
glomerular filtration rate <60 ml·min -1·(1.73 m 2) -1 and Hb≤90 g/L were the main
risk factors for
heart failure . Age over 70 years and ALB≤30 g/L were the main
risk factors for
death (All P<0.05).
Conclusion: There exist significant differences in general condition,
foot ulcer , and outcome in DFU
patients infected with rare
bacteria strains .