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Neoadjuvant chemoimmunotherapy combined with surgery for patients with non-small-cell lung cancer staged as ⅢA / 中华胸心血管外科杂志

Fenghuan SUN; Jie YANG; Tao GE; Haoran XIA; Jie DAI; Xiaogang LIU; Jiaqi LI; Likun HOU; Liang DUAN; Chunyan WU; Yuming ZHU; Gening JIANG; Peng ZHANG.
Artículo en Zh | WPRIM | ID: wpr-912316

Objective:

To explore the efficacy and safety of neoadjuvant chemoimmunotherapy combined with surgery for stage ⅢA NSCLC patients.

Methods:

Six patients with NSCLC who were diagnosed as ⅢA and received two cycles of neoadjuvant chemoimmunotherapy and surgery between September 2019 and January 2020 were described in this study.

Results:

Five of them experienced AEs during neoadjuvant therapy. All of them received surgery and achieved an MPR of 50%. No viable tumor cells were found in the tissues of one patient. One patient with a small bronchopleural fistula after lobectomy.

Conclusion:

Neoadjuvant chemoimmunotherapy combined with surgery for stage ⅢA NSCLC patients is safe and efficient. Long-term outcomes of neoadjuvant chemoimmunotherapy combined with surgery should be further validated.
Biblioteca responsable: WPRO