Chronic kidney disease (CKD)-
mineral and
bone disorder (
CKD-MBD) is a common complication of CKD, often accompanied by extra-skeletal calcification in
adult patients. As increased
vascular calcification is predicted to increase cardiovascular
mortality and
morbidity, the revised
Kidney Disease Improving Global Outcomes guidelines recommend avoiding
calcium-containing
phosphate chelators. However, extra-skeletal calcification is less commonly noticed in pediatric
patients. Here, we
report our experience of such a complication in pediatric
patients receiving
maintenance peritoneal dialysis. Extra-skeletal calcification was noticed at the
corneas, pelvic cavity, and soft
tissues of the lower
leg in 4 out of 32
patients on
maintenance peritoneal dialysis. These
patients experienced the
aggravation of extra-skeletal calcifications during
peritoneal dialysis, and 2 of them underwent excisional operations. It is required to monitor extra-skeletal calcifications in
children on
kidney replacement therapy.