Background@#
Metabolic syndrome has been known as a
risk of
cardiovascular disease. Meanwhile,
high sensitivity C-reactive protein (
hs-CRP) is used as a predictor of
cardiovascular disease. In this
paper, we aimed to investigate the
association between
hs-CRP and
metabolic syndrome.
Method:
A total of 7,633 were chosen as the study
population from the 7th
Korea National Health and Nutrition Examination Survey dataset (2016–2017). Our dependent variable was whether an individual had
metabolic syndrome or not, and the independent variable of interest was
hs-CRP which was categorized into three groups. The
chi-square tests and hierarchical
logistic regression analyses reflecting
survey characteristics were conducted. All analyses were stratified by
gender. @*Results@#According to the adjusted model with all covariates, compared to individuals having the low
risk of
hs-CRP, those having its average
risk were more likely to have
metabolic syndrome in
men (
odds ratio [OR], 1.41; 95%
confidence interval [CI], 1.12–1.76) and
women (OR, 1.69; 95% CI, 1.33–2.16). Individuals having the high
risk was not significantly different in
men; however, they were more likely to have
metabolic syndrome in
women (OR, 2.03; 95% CI, 1.28–3.23). @*Conclusion@#In an upcoming
aging society, it is important to reduce the
risk of
metabolic syndrome to improve
population health. This study suggests that
hs-CRP may be used as a marker of the
risk of
metabolic syndrome in a
gender-specific way, thereby contributing to enhancing
awareness of the
risk of
metabolic syndrome among the general public.