Intestinal flora imbalance
plays a certain
role in the development and progression of
liver cancer , while
probiotics have a certain impact on
liver cancer , both of which are the focus of clinical
research . This article introduces the mechanism of action of
intestinal flora imbalance in the pathogenesis of
liver cancer and the preventive effect of
probiotics against
liver cancer .
Intestinal flora imbalance can participate in the pathological process of
liver cancer by activating
Toll-like receptor 4 , regulating the level of metabolites, producing
endotoxin , and inducing
bacterial translocation and intestinal bacterial overgrowth, while
probiotics can effectively prevent
liver cancer by maintaining
enterohepatic circulation , enhancing immune function, promoting the
reproduction of intestinal
probiotics , and reducing the
toxicity of
carcinogens , which can be further studied as the focus of subsequent
liver cancer prevention in clinical practice.