Background@#Clinical implications of elevated
fasting triglycerides (FTGs) and non-
fasting triglycerides (NFTGs) in
acute ischemic stroke (AIS) remain unknown. We aimed to elucidate the correlation and
clinical significance of FTG and NFTG levels in AIS
patients. @*
Methods@#Using a multicenter prospective
stroke registry, we identified AIS
patients hospitalized within 24 hours of onset with available NFTG results. The primary outcome was a composite of
stroke recurrence,
myocardial infarction, and all-cause
mortality up to one year. @*Results@#This study analyzed 2,176
patients. The
prevalence of
fasting and non-
fasting hypertriglyceridemia was 11.5% and 24.6%, respectively.
Multivariate analysis revealed that younger age, diabetes, higher
body mass index and initial systolic
blood pressure were independently associated with both
fasting and non-
fasting hypertriglyceridemia (all P < 0.05).
Patients with higher quartiles of NFTG were more likely to be
male, younger, eversmokers, diabetic, and have
family histories of premature
coronary heart disease and
stroke (all P < 0.05).
Similar tendencies were observed for FTG. The composite outcome was not associated with FTG or NFTG quartiles. @*Conclusion@#The
fasting and non-
fasting hypertriglyceridemia were prevalent in AIS
patients and showed
similar clinical characteristics and outcomes. High FTG and NFTG levels were not associated with occurrence of subsequent clinical events up to one year.