A total of 33
pesticides have been banned from
Chinese medicinal materials and decoction pieces(
plants) according to
Chinese Pharmacopoeia(2020 edition). According to the chemical structures, they are mainly divided into seven categories
organophosphorus compounds, organochlorines,
carbamates,
amidines, sulfonylureas, phenylpyrazoles, and
ethers. These banned
pesticides exhibit neurotoxicity, reproductive
toxicity,
immune system toxicity, teratogenicity,
carcinogenesis, and
mutagenesis, seriously damaging
human and
animal health. They
affect not only the quality and
safety of traditional
Chinese medicines and resulting products, but also their competitiveness in the international market. Due to the numerous varieties of traditional
Chinese medicines and their complex
substrates, it is necessary to establish a universal and highly sensitive
method for
pesticide residue detection. This
review systematically summarized the residual status,
toxicity, and
analytical methods of banned
pesticides in traditional
Chinese medicines, and forecasted the prospects of different
analytical techniques, so as to provide reference for further
safety and
risk assessment of banned
pesticide residues in traditional
Chinese medicines, thus ensuring the safe
production of traditional
Chinese medicines.