Areca catechu L. medicinal materials and their preparations are widely used in clinical practice. Betelnut
polyphenol is one of the main chemical components with
antioxidant, anti-inflammatory, and antibacterial effects. With continuous increase of high
altitude activities,
tissue oxidative damage caused by high
altitude hypoxia seriously
affects the
ability to
work, and the studies on anti-
hypoxia drugs are particularly important. Recent studies have shown that betelnut
polyphenols have protective effects on
oxidative stress injury caused by
hypoxia via improving
blood gas index of hypoxic organism, increasing
superoxide dismutase glutathione catalase activity, and scavenging excessive
free radicals. The effects of betelnut
polyphenols against
hypoxia and
oxidative damage protection suggest that betelnut
polyphenols can be used as potential anti-
hypoxia drugs and posses clinical prospects.