Radical
prostatectomy(RP)was commonly used in localized
prostate cancer. For
patients with adverse pathological features (APF) after RP, it was controversial about choosing
adjuvant radiotherapy or salvage
radiotherapy (SRT). Recent studies have found that early salvage
radiotherapy(ESRT) had both the same
cancer control and reduced
overtreatment compared to
adjuvant radiotherapy.
Nomogram and
Gene Classifier(GC) could predict the
risk of
recurrence after RP and contribute to choose
adjuvant radiotherapy or ESRT. PSMA
PET/CT was more sensitive to detect distant
metastasis after biochemical
recurrence, which was helpful to decide whether to implement SRT.