OBJECTIVE:
To investigate the
association of
family history of
stroke with functional outcomes in
stroke patients in
Korea.
METHODS:
A
case-control study was conducted. A total of 170
patients who were admitted to a
rehabilitation unit were included.
Risk factors for
stroke such as age,
sex,
diabetes mellitus,
hypertension,
atrial fibrillation,
smoking, high
blood cholesterol and
homocysteine level,
obesity, and
family history of
stroke were taken into account.
Stroke subtypes were the following large vessel
infarct, small vessel
infarct, embolic
infarct,
subarachnoid hemorrhage, and
intracranial hemorrhage.
Stroke severity as assessed with the
National Institutes of Health Stroke Scale (NIHSS), functional outcomes using the Korean version of the Modified Barthel index (K-MBI),
Functional Independence Measurement (FIM), and
cognitive function using the Korean version of Mini-Mental
State Examination (K-MMSE) were assessed at admission and discharge.
RESULTS:
Subjects with a
family history of
stroke were more likely to have an
ischemic stroke (90.7%) than were those without a
family history (70.9%). The K-MBI, FIM, NIHSS, and K-MMSE scores did not show significant differences between
patients with or without
family history.
CONCLUSION:
Family history of
stroke was significantly associated with
ischemic stroke, but not with functional outcomes. Other
prognostic factors of
stroke were not distributed differently between
patients included in this study with or without a
family history of
stroke.